Environment, Social and Governance Strategy

For more than 40 years, Amgen’s commitment to science and innovation has helped patients live longer, healthier lives. We support initiatives to advance health equity so that more people can experience the benefits of science, including improved access to life-saving medicines and care. We use a portfolio of approaches to address challenges to access, working with governments, patient groups, civil society and other partners.

In 2022:

• We provided $2.2 billion1 of Amgen medicines at no cost to eligible uninsured or underinsured patients in the United States through the Amgen Safety Net Foundation2.
• We provided $91 million1 of Amgen medicines at no cost to underserved patients in eight low- and middle-income countries.
• We contributed $14.9 million to supporting advancement of health equity activities, funding 111 projects with 68 organizations.

In addition to our core business of improving health outcomes through our medicines, we recognize our ability to positively impact society through our actions, investments and people. We value and are focused on doing our part to build a more just, resilient and inclusive society, both within our own workplace and in the communities where we operate.

In 2022:

• We reached more than 23 million learners and educators worldwide through the Amgen Foundation’s four core science education programs.2
• We developed an “earn-and-learn” apprenticeship program to attract, hire and upskill talent without a four-year degree in the United States as part of our OneTen coalition pledge.
• We continued to foster an inclusive environment — the percentage of women in Amgen’s global workforce has held steady for the past several years at approximately 52%, while leadership positions have grown to 45% women globally and 32% minorities in the United States.

Amgen has a longstanding objective to conduct its operations in an environmentally responsible manner, and we regularly set targets to challenge ourselves to improve. We have successfully advanced our environmental sustainability program since 2007 while increasing our global production capacity and expanding our presence to approximately 100 countries. Investing in sustainable operations can also improve efficiency and create value, including by reducing operating costs and increasing resilience.

In 2022:

• We exceeded our goals for carbon, water and waste reductions and are on track to achieve our 2027 ambition.
• We issued an inaugural $750 million green bond to advance our environmental goals.
• The Science Based Targets initiative approved our greenhouse gas emissions reduction goals to align with a 1.5°C future.

Our business is built on an unwavering commitment to integrity and compliance, which is demonstrated daily by our employees through their words, decisions and actions. We seek to maintain and strengthen the trust of the stakeholders we serve. This is not only the right thing to do, but also essential for the long-term health of Amgen and the patients and stakeholders we serve. In 2022:

In 2022:

• 100% of employees were trained on the Code of Conduct.
• 92% of employees in a staff survey said they are aware of how to seek guidance on ethical matters.
• We included an ESG target in the Company’s annual incentive plan performance goals to hold ourselves accountable to our 2027 environmental sustainability goals and to expand the number of leaders directly responsible for action in support of our diversity, inclusion and belonging program.

1. The Heart-Lung Foundation. The heart report 2019 . The statement that two million people in Sweden live with cardiovascular disease refers to 2018 and is based on specially ordered statistics from the National Board of Health and Welfare, dnr 30687/2018.
2. Hansson GK. Atherosclerosis (hardening of the arteries). Internet medicine. Updated 2020-07-12
3. Fact sheet. Cardiovascular diseases (CVDs) . World Health Organization (WHO). 2021-06-11.
4. 1177 The care guide. Heart attack . Updated 2021-06-23.
5. 1177 The care guide. Stroke . Updated 2020-02-11.